Pharmacokinetic Characterization of the Hemophilia A Population in Spain Using myPKFiT®

Inclusion Criteria: * Male patients. * Age between 1 and 65 years old. * Patients diagnosed with Hemophilia A who are on prophylactic treatment with Advate® or Adynovi® or adjusted with myPKFIT. * Patients older than 18 who have signed the informed consent form. * In the case of mature minors, in addition to the consent signed by the legal guardian, an assent of the minor must be obtain. * In the case of patients legally incapable for giving their consent, their primary caregiver will consent as the patient's legal guardian. Exclusion Criteria: * Withdrawal of informed consent. * Patients with any medical or psychological condition that according to the researcher's criteria prevents them from following the usual clinical practice procedures. * Patients with concomitant diagnosis of other haemostasis disorders. * Patients being treated for induction of immunologic tolerance at the time of inclusion.