Investigation of the acute and chronic effects of Supradyn® Energy 3RDA on subjective ratings of 'fatigue/stress', substrate metabolism and blood biomarkers of recovery, as a consequence of exercise and metabolically demanding cognitive tasks.
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Acute treatment effects on energy expenditure/metabolism during physical stress
Timeframe: Measures taken following acute treatment during exercise (45 minutes post acute treatment)
Acute treatment effects on energy expenditure/metabolism during mental stress
Timeframe: Measures taken following acute treatment during cognitive task performance (135 minutes post acute treatment)
Chronic treatment effects on energy expenditure/metabolism during physical stress
Timeframe: Measures taken following 28 days' chronic treatment, during exercise performance
Chronic treatment effects on energy expenditure/metabolism during mental stress
Timeframe: Measures taken following 28 days' chronic treatment, during cognitive task performance
Acute treatment effects on subjective arousal/stress/fatigue ratings as assessed by visual analogue scales during physical stress
Timeframe: Following acute treatment, measures taken before, after and every 10 minutes during 30 minute exercise period
Acute treatment effects on subjective arousal/stress/fatigue ratings as assessed by visual analogue scales during mental stress.
Timeframe: Following acute treatment, measures taken before, after and every 10 minutes during 30 minute cognitive task period
Chronic (28 days) treatment effects on subjective arousal/stress/fatigue ratings as assessed by visual analogue scales, during physical stress
Timeframe: Following 28 days' treatment, measures taken before, after and every 10 minutes during 30 minute exercise period
Chronic (28 days) treatment effects on subjective arousal/stress/fatigue ratings as assessed by visual analogue scales, during mental stress
Timeframe: Following 28 days treatment, measures taken before, after and every 10 minutes during 30 minute cognitive task period
Acute treatment effects on recovery biomarkers
Timeframe: Following acute treatment, taken at baseline and following exercise (75 minutes post-dose) and cognitive task performance (165 minutes post-dose). Then at 24h and 48hours post-exercise.
Chronic (28 days) treatment effects on recovery biomarkers
Timeframe: Following 28 days treatment, taken at baseline, following exercise and cognitive task performance. Then at 24h and 48hours post-exercise.