Use of Apremilast in Patients Who Are Dissatisfied With Stable Maintenance Topical Therapy

Inclusion Criteria: * Subjects must be in general good health as judged by investigator * Female of childbearing potential (FCBP) must have a negative pregnancy test at screening and Baseline. * FCBP must use an approved method of contraception as outlined in the protocol. * Male subjects who engage in activity in which conception is possible must use barrier contraception as defined in the protocol. * 18 years of age or older * Understand and voluntarily sign the Informed Consent * Able to adhere to study visit schedule * Moderate plaque type psoriasis as define by a a PGA of 3 * BSA 0f 5-10% or a DLQI score of 7 or more * History of uncontrolled plaque psoriasis after either stable dose of high potency topical steroids for 2 weeks or mid-potency steroids for 4 weeks within the last 6 months Exclusion Criteria: * Any clinically significant disease as determined by the investigator or major disease that is currently uncontrolled * Any condition, including the presence of laboratory abnormalities, which would place the subject at unacceptable risk * Prior history of suicide attempt at any time in the subject's lifetime prior to screening or randomization, or major psychiatric illness requiring hospitalization within the last 3 years * Pregnant or breastfeeding, FCBP who are not willing to use acceptable birth control methods. * Active substance abuse or a history of substance abuse within 6 months prior to screening. * Malignancy or history of malignancy except fo treated (…