Endocrine and Neural Control of Eating in Women (NCT02994420) | Clinical Trial Compass
CompletedNot Applicable
Endocrine and Neural Control of Eating in Women
Switzerland50 participantsStarted 2016-07
Plain-language summary
The purpose of this study is to better understand how female sex hormones influence the food intake in the gut system through the release of satiety hormones as well as through central regulative mechanisms in the brain that subsequently contribute to the control of eating in healthy women at different stages of the ovarian cycle.
Who can participate
Age range18 Years – 35 Years
SexFEMALE
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Inclusion Criteria:
* Physically and psychiatrically healthy women
* Stable body weight (no changes ≥ 5 kg in past year)
* Age 18-35 years
* Regular menses (26-32 d cycles)
* Right-handed
* German language fluency
* Signed informed consent
Exclusion Criteria:
* Life history of eating disorders
* Aversion to the test foods
* Pacemaker or neurostimulator
* Hearing aid
* Surgery to head or heart
* Potential metal parts in body (pacemakers, metal splinters, gun wounds, shrapnel or surgical clips)
* Neurological or psychiatric problems or serious brain injury (such as alcohol or drug abuse, depression, schizophrenia, bipolar disorders, anxiety disorder, claustrophobia, Parkinson's disease, multiple sclerosis, epilepsy)
* High blood pressure, low blood pressure, history of heart disease, irregular heart rate
* Emphysema, chest or respiratory problems (including difficulty breathing through the nose)
* Pregnancy, nursing or pregnancy planned in next three months
* History of gall bladder disease or symptoms (right upper abdominal quadrant pain after meals)
* Polycystic ovary syndrome, as gauged by testosterone levels
* Allergy or sensitivity to lactose
* Allergy to quinine
* Current or previous malignancies
* History of difficult blood sampling