Restoring the Beneficial Effects of Enterohepatic Bile Salt Signalling by Chyme Reinfusion in Patients With a Double Enterostomy

Inclusion Criteria: * Age equal or above 18 years old * Temporary double enterostomy treated by chyme reinfusion as a routine primary care * Downstream bowel of at least 25 cm of healthy small bowel, accessible by a stoma, and suitable for chyme reinfusion and ileal biopsy * In case of enterocutaneous fistula, diagnosis of fistula origin and localization confirmed by additional medical imaging (computerized tomography/fistulography) * Written informed consent. Exclusion Criteria: * Patients with a mental disability * Pregnancy or lactation * Hepatocellular carcinoma * Blood coagulation disorders * Shock of any cause * Patients subject to major legal protection (safeguarding justice, guardianship, trusteeship), persons deprived of liberty