CARdioprotection in Myocardial Infarction (NCT02967965) | Clinical Trial Compass
UnknownNot Applicable
CARdioprotection in Myocardial Infarction
France2,000 participantsStarted 2013-11-30
Plain-language summary
CARIM is a prospective cohort of 2,000 patients with a first myocardial infarction and undergoing reperfusion therapy. Therefore, male and female patients older than 18 years and younger than 90 years with onset of chest pain of less than 12 hours who need a primary percutaneous coronary intervention (PCI) for a ST elevation segment MI (STEMI) will be recruited.
Who can participate
Age range
18 Years – 90 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Any patient hospitalized in the cardiology department of the participating centers
* Who have signed the Informed Consent Form.
* Patient having health insurance.
* Requiring PCI for reperfusion.
* With a diagnosis of a first MI.
* With ST segment elevation and/or Q wave at admission.
* With troponin elevation.
* Seen within the first 12 hours after symptom onset.
* Aged between 18 and 90 years.
Exclusion Criteria:
* Refusal of the patient.
* In case of poor echogenicity, the participation of the patient will be stopped.
* Patient with diagnosis of previous MI, or hypertrophic or dilated cardiomyopathy, or significant valvular heart disease, or chronic atrial fibrillation, or pace maker or any permanent implanted device susceptible to interfere with LV remodeling.
* Patient with preexisting heart failure.
* Patient with any previous cardiac surgery.
* Patient with previous chemotherapy susceptible to induce LV remodeling (anthracyclines).
* Patient with an associated short-time life-threatening disease.
* Pregnant or breast-feeding patient.
* Contra-indication to MRI (claustrophobia, pacemaker or any other metallic implants, creatinin clearance \< 30mL/min/1.73m2 MDRD).
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.