Misoprostol 400 µg Versus 200 µg for Cervical Ripening in 1st Trimester Miscarriage

Inclusion Criteria: * All patients admitted at the Gynecological emergency Unit at Hospital de Clínicas de Porto Alegre scheduled for uterine evacuation with \<12 weeks of gestation. Exclusion Criteria: * patients who do not wish to participate in the project; * patients with ectopic pregnancy; * patients with comorbidities (heart failure congestive, chronic obstructive pulmonary disease); * patients with hypovolemic shock; * patients with cervical incompetence; * patients with infected miscarriage/abortion (presence of fever, pus from the cervix, leukocytosis \[\> 14000\]); * patients with twin pregnancy; * patients with Marfan syndrome; * patients allergic to misoprostol; * patients with coagulopathy; * patients with opening of cervical internal os (4 mm of dilatation at the time of consultation); * patients with previous surgery of the cervix (conization); * patients with concomitant use of IUDs.