RecruitingNot Applicable

Early PKD Observational Cohort Study

United States250 participantsStarted 2016-04

Plain-language summary

This observational study will collect blood and urine and clinical information from individuals with early-stages of polycystic kidney disease (PKD), their unaffected siblings and normal volunteers to create a biobank, also called a biorepository. The long-term goal is to develop new knowledge on biological markers or biomarkers that indicate changes in the disease progression. An understanding of biomarkers for early renal cyst growth will benefit PKD patients as new therapies are being developed and tested.

Who can participate

Age range4 Years – 35 Years

SexALL

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Inclusion Criteria: * Inclusion for early stage autosomal dominant polycystic kidney disease (ADPKD): * Family history of PKD * All races and ethnic groups * Glomerular filtration rate (GFR) \>80 ml/min per 1.73 m2 * Inclusion for Healthy Volunteers: * Male or female with no family history of kidney disease * All races and ethnic groups * Normal GFR Exclusion Criteria: * Non-insulin or insulin-dependent diabetes mellitus * Systemic illness (i.e.systemic lupus erythematosus, vasculitis) * Unable to provide written informed consent * Unavailable for magnetic resonance imaging (MRI) and blood/urine collection

What they're measuring

Collect blood and urine samples from affected and unaffected cohorts for basic and translational research

Timeframe: 10 years

Trial details

NCT IDNCT02936791

SponsorUniversity of Kansas Medical Center

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2030-06

Contact for this trial

Cathy Creed, RN

913-588-0053 ccreed@kumc.edu

View on ClinicalTrials.gov More Polycystic Kidney Disease trials