Metabolic Effects of Egg Protein and Unsaturated Fat Intakes in Subjects With Hypertriglyceridemia (NCT02924558) | Clinical Trial Compass
CompletedNot Applicable
Metabolic Effects of Egg Protein and Unsaturated Fat Intakes in Subjects With Hypertriglyceridemia
28 participantsStarted 2015-02
Plain-language summary
The goal of this study is to evaluate the effects of replacing some refined starches and added sugars with a combination of egg protein and unsaturated fatty acids on markers of cardiometabolic health in men and women with hypertriglyceridemia.
Who can participate
Age range21 Years – 70 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Fasting TG level 150-499 mg/dL
* Body mass index (BMI) 25.0-39.9 kg/m2
* Score of 7-10 on Vein Access Scale
* Normally active and judged to be in general good health on basis of medical history and routine laboratory tests
Exclusion Criteria:
* Fasting blood glucose ≥126 mg/dL or known type 1 or type 2 diabetes mellitus
* Atherosclerotic cardiovascular disease
* Recent history or current significant renal, pulmonary, hepatic, biliary, or gastrointestinal disease
* Abnormal lab test results of clinical significance (e.g., creatinine ≥1.5 mg/dL and aspartate or alanine transaminase ≥1.5 times upper limit of normal)
* History of cancer in previous 2 years
* Uncontrolled hypertension
* Recent unstable use of anti-hypertensive medication, thyroid hormone replacements, and/or medications known to substantially influence carbohydrate metabolism
* Recent use of certain blood pressure medications (e.g., beta-adrenergic blockers and/or high-dose thiazide diuretics)
* Recent use of lipid-altering drugs (e.g., statins, bile acid sequestrants, cholesterol absorption inhibitors, or fibrates)
* Recent use of diabetes medication (e.g., alpha-glucosidase inhibitors, biguanides and biguanide combinations, bile acid sequestrants, thiazolidinediones, dipeptidyl peptidase-4 inhibitors, meglitinides, and sulfonylureas and combination sulfonylureas)
* Recent use of lipid-altering foods, herbs, or dietary supplements (e.g., niacin, sterol/stanol products, dietary fiber suppl…
What they're measuring
1
Matsuda composite index of insulin sensitivity (MISI)
Timeframe: 3 weeks
Trial details
NCT IDNCT02924558
SponsorMidwest Center for Metabolic and Cardiovascular Research