The purpose of the study is to assess: 1 safety and tolerability of adenovirus serotype 26 (Ad26) prime and Modified Vaccinia Ankara (MVA) boost versus placebo in participants on suppressive antiretroviral therapy (ART) that was initiated during acute Human Immunodeficiency Virus (HIV) infection; 2) Measure the frequency and duration of sustained viremic control after receiving Ad26 prime/MVA boost or placebo, defined as greater than 24 weeks with plasma HIV ribonucleic acid (RNA) lesser than (\<)50 copies/ml after antiretroviral (ARV) analytical treatment interruption (ATI).
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Percentage of Participants With Grade 3 or 4 Solicited Local Adverse Events (AEs)
Timeframe: Up to Week 49 (7 days post each vaccination)
Percentage of Participants With Grade 3 or 4 Solicited Systemic AEs
Timeframe: Up to Week 49 (7 days post each vaccination)
Percentage of Participants With Grade 3 or 4 Unsolicited AEs
Timeframe: Up to Week 52 (28 days after each vaccination)
Percentage of Participants With Grade 3 or 4 Related AEs
Timeframe: Up to Week 52 (28 days after each vaccination)
Percentage of Participants With Solicited Local AEs for 7 Days After Each Vaccination
Timeframe: Up to Week 49 (7 days post each vaccination)
Percentage of Participants With Solicited Systemic AEs for 7 Days After Each Vaccination
Timeframe: Up to Week 49 (7 days after each vaccination)
Percentage of Participants With Unsolicited AEs 28 Days After Each Vaccination
Timeframe: Up to Week 52 (28 days after each vaccination)
Percentage of Participants With Related AEs and Serious Adverse Events (SAEs)
Timeframe: Up to Week 52 (28 days after each vaccination)
Percentage of Participants With AEs Leading to Discontinuation of Study Vaccination
Timeframe: Up to Week 96
Percentage of Participants With AEs
Timeframe: Up to Week 52 (28 days after each vaccination)
Percentage of Participants With Worst Laboratory Toxicity Grades 1, 2, 3, and 4 and Non-graded Serum Chemistry Abnormalities
Timeframe: Up to Week 96
Percentage of Participants With Worst Laboratory Toxicity Grade 1 and Non-graded Hematology Abnormalities
Timeframe: Up to Week 96
Percentage of Participants With Sustained Viremic Control (Human Immunodeficiency Virus [HIV] Ribonucleic Acid [RNA] Less Than [<]50 Copies Per Milliliter [Copies/mL]) During ATI Phase
Timeframe: From Week 60 to Week 96
Duration of Sustained Viremic Control With HIV RNA <50 Copies/mL During ATI Phase
Timeframe: From Week 60 to Week 96