Resveratrol in Knee Osteoarthritis

Inclusion Criteria: * Age ≥ 40 years-old * Knee osteoarthritis fulfilling 1986 American College of Rheumatology (ACR) criteria * Pain on numeric rating scale ≥ 40/100 * Symptom duration ≥ 1 month * Kellgren and Lawrence X-Ray score 1, 2 or 3 * Written consent obtained * Health insurance cover Exclusion Criteria: * History of symptomatic crystal or inflammatory arthritis * Knee surgery ≤ 1 year * Knee trauma ≤ 2 months * Knee intra-articular injections of corticosteroids and/or hyaluronic acid ≤ 2 months * Neurologic disorders involving the lower limbs * Patient not understanding and not speaking french * Participation in another biomedical research * Contraindication to resveratrol or hypersensitivity to any of its constituents * Current use of intramuscular, intravenous or oral corticosteroids * Uncontrolled diseases that may require intramuscular, intravenous or oral corticosteroids * Current use of anticoagulants