Cerebellar Transcranial Direct Current Stimulation and Aphasia Treatment (NCT02901574) | Clinical Trial Compass
CompletedNot Applicable
Cerebellar Transcranial Direct Current Stimulation and Aphasia Treatment
United States32 participantsStarted 2016-09-19
Plain-language summary
People with post-stroke aphasia are left with some degree of chronic deficit for which current rehabilitative treatments are variably effective. This study investigates the behavioral and neural effects of multiple consecutive cerebellar tDCS sessions coupled with computerized naming therapy in stroke survivors with aphasia.
Who can participate
Age range18 Years – 100 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Participants must have sustained a left hemisphere stroke.
* Participants must be fluent speakers of English by self-report.
* Participants must be capable of giving informed consent or indicating another to provide informed consent.
* Participants must be age 18 or older.
* Participants must be premorbidly right handed.
* Participants must be at least 6 months post stroke.
* Participants must have an aphasia diagnosis as confirmed by the Boston Diagnostic Aphasia Examination (BDAE) Short Form.
* Participants must achieve at least 65% accuracy on screening task (comparable to treatment task) on 1 of 3 attempts
Exclusion Criteria:
* Participants with lesion involving the right cerebellum
* Previous neurological or psychiatric disease.
* Seizures during the previous 12 months.
* Uncorrected visual loss or hearing loss by self-report.
* Use of medications that lower the seizure threshold (e.g., methylphenidate, amphetamine salts).
* Use of N-methyl-D-aspartate receptor (NMDA) antagonists (e.g., memantine).
* \> 80% (140 out of 175) correct responses on the Philadelphia Naming Test at baseline.
* History of brain surgery or any metal in the head.
* Scalp sensitivity (per participant report).
What they're measuring
1
Change in Accuracy of Naming Untrained Pictures (Philadelphia Naming Test:PNT) Pre-treatment to Post-treatment
Timeframe: Before and after 15 sessions (3-5 sessions per week; up to 5 weeks) of treatment.