UnknownNot Applicable

The Correlation Between the n-6:n-3 Ratio and Inflammatory Markers in Small for Gestational Age (SGA) Infants Compared With Appropriate for Gestational Age (AGA) Infants

Israel60 participantsStarted 2018-10-02

Plain-language summary

Numerous studies have recommended the use of n-3 PUFA supplementation during human pregnancy and lactation for the prevention of preterm birth, beneficial effects on fetal development, visual and cognitive development and other functional outcomes of the infants. The aim of the present study is to assess the correlation between ratio of n-3:n-6 fatty acid and inflammation markers in SGA infants compared with appropriate for gestational age (AGA) infants. The investigators hypothesize that in SGA infants n-3 and n-6 fatty acid concentrations in cord blood will differ from those observed in AGA and might correlate with the level of circulating mediators.

Who can participate

Age range18 Years – 60 Years

SexFEMALE

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Inclusion Criteria: * Mothers of SGA infants ( above 35 week of gestation) * Mothers of term and near-term AGA infants Exclusion Criteria: * Maternal chronic diseases, smoking, diabetes, alcohol use, pregnancy-associated hypertension and pre-eclampsia * Neonatal depression * Congenital malformations * Intrauterine infections * Chromosomal aberrations * Mothers interested in cord blood banking

What they're measuring

Cord blood analysis

Timeframe: at time of delivery

Trial details

NCT IDNCT02887664

SponsorTel-Aviv Sourasky Medical Center

Sponsor typeOTHER_GOV

Study typeOBSERVATIONAL

Primary completion2020-12

Contact for this trial

Dror Mandel, MD

+97236925690 drorm@tlvmc.gov.il

View on ClinicalTrials.gov More Small for Gestational Age Infants trials