A Study Comparing Tazarotene Cream 0.05% to TAZORAC® (Tazarotene) Cream 0.05% and Both to a Place⦠(NCT02886702) | Clinical Trial Compass
CompletedPhase 3
A Study Comparing Tazarotene Cream 0.05% to TAZORACĀ® (Tazarotene) Cream 0.05% and Both to a Placebo Control in the Treatment of Plaque Psoriasis
United States855 participantsStarted 2016-09-19
Plain-language summary
A Multi-Center, Double-Blind, Randomized, Vehicle-Controlled, Parallel-Group Study Comparing Tazarotene Cream 0.05% to TAZORACĀ® (tazarotene) Cream 0.05% and Both Active Treatments to a Vehicle Control in the Treatment of Stable Plaque Psoriasis
Who can participate
Age range18 Years
SexALL
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Inclusion Criteria:
* Have a definite clinical diagnosis of stable (at least 6 months) plaque psoriasis, involving at least 2% and no more than 20% of the body surface area (BSA) (not including the scalp and intertriginous areas)
* Have a minimum plaque elevation at the target lesion site of at least moderate severity (grade ā„ 3 on the Psoriasis Area Severity Index \[PASI\]). The most severe lesion at baseline should be identified as the target lesion
* Have an Investigator's Global Assessment (IGA) of disease severity of at least moderate (score ā„ 3) as an overall assessment of all lesions to be treated.
Exclusion Criteria:
* A female subject who is pregnant, nursing, planning a pregnancy, or does not agree to use an acceptable form of birth control within the study participation period
* Have a current diagnosis of unstable forms of psoriasis in the treatment area, including pustular, guttate, exfoliative or erythrodermic psoriasis
* Have a history of psoriasis unresponsive to topical treatments