Cardiac Output Autonomic Stimulation Therapy for Heart Failure (COAST-HF) - Human NeuroCatheter Study

Inclusion Criteria: * Stable symptomatic heart failure - New York Heart Association Class II or III * Normal Sinus Rhythm Exclusion Criteria: * Unable to gain arterial or venous access using standard percutaneous techniques * New York Heart Association Class IV * Patient taking amiodarone or other anti-arrhythmic therapy * Patients with implanted pacemaker, ICD, or CRT device * Patients who had CABG, PCI or enzyme-positive MI within prior month * Patients with pre-existing carotid artery or cerebral disease * Patients with hypertrophic obstructive cardiomyopathy or infiltrative cardiomyopathy (e.g. amyloidosis, sarcoidosis) * Patients who have been hospitalized for heart failure and who required the use of heart failure IV therapy within 30 days before enrollment (measured from release) * Patients with current or prior vagal nerve simulator * Patients with renal failure * Patients with hepatic failure * Patients with narrow angle glaucoma * Patients who are pregnant * Patients with a life expectancy \< 12 months per physician judgment * Patients with allergy to fentanyl, midazolam, propofol, eggs, egg products, soybeans, or soy products