CompletedNot Applicable

A Study to Compare Adaptive Support Ventilation vs. Volume Controlled Ventilation for Management of Respiratory Failure in Patients With Neuroparalytic Snake Envenomation

India50 participantsStarted 2016-12

Plain-language summary

Neuroparalytic snake envenomation results in severe muscle weakness and respiratory failure. Treatment requires administration of anti-snake venom and supportive care in the form of invasive mechanical ventilation. Whether using adaptive support ventilation (a closed loop mode of ventilation) in comparison to volume controlled ventilation will shorten the duration of ventilation remains undetermined. The current study is planned to compare adaptive support ventilation (ASV) mode of ventilation versus volume controlled ventilation (VCV) during invasive mechanical ventilation for the management of respiratory failure secondary to neuroparalytic snake envenomation.

Who can participate

Age range12 Years – 90 Years

SexALL

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Inclusion criteria

✓. Need for invasive mechanical ventilation for management of respiratory failure
✓. age group of 12 to 90 years
✓. ability to provide informed consent to participate in the study

Exclusion criteria

✕. Cardiorespiratory arrest requiring cardiopulmonary resuscitation
✕. pregnancy
✕. failure to provide informed consent

What they're measuring

Liberation from mechanical ventilation

Timeframe: 28 days after discharge

Trial details

NCT IDNCT02877498

SponsorPost Graduate Institute of Medical Education and Research, Chandigarh

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-01-31

View on ClinicalTrials.gov More Snake Envenomation trials