Two Second-Generation Trabecular Micro-bypass Stents to Treat Glaucoma Subjects on One Hypotensive Medication

INCLUSION CRITERIA: Screening Exam Inclusion Criteria: * Phakic patients or pseudophakic patients with posterior chamber intraocular lenses (PC-IOLs). * Primary open-angle glaucoma (including pigmentary or pseudoexfoliative). * Cup-to-disc ratio ≤ 0.9. * Visual field defects, or nerve abnormality characteristic of glaucoma. * One topical hypotensive medication at time of screening exam. * Intraocular pressure (IOP) \> 18 mmHg and ≤ 30 mmHg (medicated) at screening exam. * Study eye BCVA 20/100 or better. * Normal angle anatomy as determined by gonioscopy. * Absence of peripheral anterior synechia (PAS), rubeosis or other angle abnormalities that could impair proper placement of stent. Baseline Exam Inclusion Criteria: * Subject has completed appropriate medication washout. * Mean IOP \> 22 mmHg and ≤ 38 mmHg after anti-glaucoma medication washout period. EXCLUSION CRITERIA: Screening Exam Exclusion Criteria: * Aphakic patients or pseudophakic patients with anterior chamber IOLs (AC-IOLs). * Prior stent implantations (study eye). * Traumatic, uveitic, neovascular, or angle-closure glaucoma; or glaucoma associated with vascular disorders. * Functionally significant visual field loss, including severe nerve fiber bundle defects such as Bjerrum scotoma. * Prior incisional glaucoma surgery. * Prior SLT within 90 days prior to screening. * Prior ALT. * Iridectomy or laser iridotomy. * Ineligibility for ocular hypotensive medication washout period as determined by the investi…