Long Term Treatment of Panic Disorder With Clonazepam or Paroxetine

Inclusion Criteria: * Diagnosis of panic disorder, with or without agoraphobia according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, text revision (DSM-IV-TR) criteria, as determined by a structured clinical interview. * At least two panic attacks in the week preceding their inclusion in the study. Exclusion Criteria: * Patients unable or unwilling to provide written informed consent. * Did not complete all the evaluations before study initiation. * Had comorbidities that could affect clinical evaluation including drug abuse, neurological disorders, or severe personality disorder.