Efficacy and Safety of b-2Cool on Adults With Joint Discomfort

Inclusion Criteria: * Adults between 40 and 75 years old. * Subject who suffers mild joint discomfort (value between 3 and 5 VAS scale for a minimum of 6 months). * Subject that after reading and understanding the study's protocol has provided written informed consent to participate in the study. * Subjects willing to keep stable eating and activity patterns during the duration of the study. * Subjects who use other therapies for joint discomfort, such as exercise, heat / cold, joint protection and physiotherapy / occupational therapy agree to follow the treatments avoiding changes in the frequency or intensity of them and reporting them at baseline and during follow-ups. * Subjects agree not start any new therapy during the study period. * Subjects who have lateral or longitudinal knee synovial effusion according to the index OMERACT (Outcome Measures in Rheumatology) . Exclusion Criteria: * Active rheumatoid arthritis, diagnosed osteoarthritis or any other inflammatory arthritic condition that researchers consider non appropriate. * Being pregnant or lactating. * Be waiting for joint surgery or major surgery in the next 8 months * Joint injury in the last 4 months in the area osteoarthritis-affected (i.e. meniscal tear) * Having underwent reconstructive surgery on the cartilage of the affected knee * Background of peptidic ulcer and other symptomatic/active disorders of the intestinal tract that may interfere with product under evaluation . * History of congestive heart …