TRANscatheter or SurgIcal Aortic Valve ReplacemenT in All-Comers With Severe Aortic Valve Stenosis

Inclusion Criteria: * Age must be at least 19 and less than 75 years old * Severe aortic valve stenosis with echocardiographically derived criteria: mean gradient \> 40mmHg or jet velocity greater than 4.0 m/s AND an initial aortic valve area (AVA) of ≤ 0.8 cm2. Echocardiogram must be within 3 months of the date of the procedure * Patient is symptomatic from his/her aortic valve stenosis, as demonstrated by NYHA class II or greater. * The patient or guardian agrees to the study protocol and the schedule of clinical and angiographic follow-up, and provides informed, written consent, as approved by the appropriate Institutional Review Board/Ethical Committee of the respective clinical site. Exclusion Criteria: * Life expectancy \<1 year due to medical illness * Suspected Malignancy * Inoperability evaluated by surgeon * Concomitant severe coronary artery disease not amenable for percutaneous coronary intervention * Concomitant severe mitral valve or significant aorta disease requiring surgery * Active bacterial endocarditis within 6 months of procedure * Leukopenia (WBC\<3000 cell/mL), acute anemia (Hgb\<8g/dL), thrombocytopenia (platelet \< 50000 cell/mL) * Intracardiac thrombus * A known contraindication or hypersensitivity to all anticoagulation regimens, or inability to be anticoagulated for the study procedure. * Native aortic annulus size \< 18 mm or \> 25 mm as measured by echocardiogram. * Expectation that patient will not improve despite treatment of aortic stenosis…