Frequency Of MCP-1 And CCR2 Gene Polymorphisms And Its Effect On Gene Expression In Patients With AgP

Inclusion Criteria: * Periodontally H control group had \< 3mm PD, \< 2 GI and no signs of interproximal attachment loss and a history of periodontal disease. * The AgP group included individuals diagnosed with localized AgP (LAgP) or generalized AgP (GAgP) who were otherwise healthy. Periodontal attachment loss ≥4 mm not involving more than two permanent teeth, other than the first molars and incisors were diagnosed with LAgP (n: 43); patients with involvement of at least three teeth, other than the first molars and incisors with an attachment loss ≥4 mm were diagnosed with GAgP Exclusion Criteria: * Patients who have any systemic diseases or conditions that could effect the periodontium * hepatitis and/or immunodeficiency virus infection * a history of periodontal treatment and antibiotic therapy within the 6 months * \< 16 teeth in their mouth * Subjects who had smoked and were ongoing orthodontic treatment were excluded.