Study to Evaluate the Safety and Efficacy of HI-BRITE Large Diameter Rigid Gas Permeable Contact Lens

Inclusion criteria: * Ametropic or irregular cornea subjects who need to wear spectacle lens or contact lens in their daily life. * Is of age at least 20 years old and no older than 65 years old capacity to volunteer. * Has read and signed the Informed Consent Form or waiver. (4) Has myopia or hyperopia -20.00D～+20.00D, astigmatism -0.25\~-4.00D, or presbyopia +1.00D～+3.50D. * Irregular cornea subjects include keratoconus, high astigmatism (\>-4.00D) or post-refractive surgery patients. * No active ocular disease, infection or any disorder of eyelids and conjunctiva. * Has reasonable expectation of improvement in visual acuity with the test lenses. * Is willing and able to follow subject instructions and meet the protocol -specified visit schedule. (If subjects missed any visit, they must be discontinued from the study.) (9) Agrees to wear the test lenses at a daily wear basis. (10) Willing to adapt wearing GP contact lens. Exclusion criteria: The subject is ineligible for entry into the study if the subject * Has any systemic disease affecting ocular health. * Is using any systemic or topical medications that will, in the Investigator's opinion. Affect ocular physiology or lens performance within one (1) week before entering this study. * Has an active ocular disease or has ever used systemic steroid or any other medicine that may affect significant on vision or healing. * Has any Grade 2 or greater finding listed in the Quantification of Slit Lamp Observations Form. Sub…