Clinical Observation of Recombinant Human Growth Hormone Injection Assisted IVF-ET in the Treatme… (NCT02801565) | Clinical Trial Compass
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Clinical Observation of Recombinant Human Growth Hormone Injection Assisted IVF-ET in the Treatment of PCOS
China208 participantsStarted 2016-02
Plain-language summary
Observe validity of Recombinant Human Growth Hormone Injection assisted in IVF-ET (in vitro fertilization and embryo transfer) treatment of PCOS (polycystic ovary syndrome) patients.
Who can participate
Age range25 Years – 35 Years
SexFEMALE
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Inclusion Criteria:
* Age between 25 and 35 years old, married female and infertile.
* BMI≥25kg/m2.
* Diagnosed as PCOS.
* No obvious chronic organic diseases, such as liver, kidney, heart, lung, thyroid, adrenal disease.
* Subjects do not take part in other clinical trial study within 3 months.
* The subjects sign the informed consent form.
Exclusion Criteria:
* BMI\<25kg/m2.
* Hyperprolactinemia and congenital adrenal cortical hyperplasia.
* Diabetes, thyroid function hyperthyroidism, thyroid dysfunction, cushing's syndrome.
* Pelvic and peritoneal tumor and tumor secreting hyperandrogenism.
* Severe acute and chronic liver and kidney disease, such as liver cirrhosis, acute and chronic renal failure, hepatitis B virus activity.
* Liver and kidney dysfunction, AST/ALT is 2.5 times higher than the normal limit, the serum of creatinine is 2 times higher than the normal level.
* Diseases affecting outcome of IVF pregnancy, eg, hydrosalpinx, hysteromyoma\>4 cm, adenomyosis, endometriosis, endometrial cyst of ovary, unilateral ovary, tuberculosis of reproductive system.
* Allergic to E. coli. expression product and its excipients.
* Being involved in other drug clinical researchers.
* The researchers consider who is not suitable for the group.