Prevention Using Exercise Rehabilitation to Offset Cardiac Toxicities Induced Via Chemotherapy (NCT02796365) | Clinical Trial Compass
CompletedNot Applicable
Prevention Using Exercise Rehabilitation to Offset Cardiac Toxicities Induced Via Chemotherapy
United States29 participantsStarted 2016-06
Plain-language summary
The purpose of this study is to identify patients at risk for future heart failure using novel markers of early cardiac damage and determine if exercise training can improve these emerging markers as well as overall fitness and quality of life.
Who can participate
Age range18 Years – 75 Years
SexALL
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Inclusion Criteria:
* Patients with cancer who are undergoing or have completed the chemotherapy drugs doxorubicin and/or trastuzumab.
* Have had a recent echocardiogram with a relative reduction in LV strain of \>10%.
* If no recent echocardiogram, have a troponin value \>0.04 ng/mL, or an increase of 0.04 ng/mL if baseline troponin is elevated.
* Age \>/= 18 years.
* Eastern Cooperative Oncology Group (ECOG) scale 0-2.
* Males and females.
Exclusion Criteria:
* Patients with an Ejection Fraction \<50%
* Patients not deemed appropriate by a cardiologist or oncologist
* Patients with an ECOG scale \>2
* Inability to perform exercise
* Patients who already report exercising \>2days per week for \>29 minutes