Parkinsonian Brain Repair Using Human Stem Cells

Inclusion Criteria: * Diagnosis of idiopathic PD with tremor, rigidity or hypokinesia as major symptoms. * A two to twenty-five-year history of PD with significant medical management or difficulty in medical management. * A definite response to levodopa compounds with inadequately relieved of symptoms, or severe secondary effects of the drug. * Good general health. * A strong will or desire to have the procedure after being fully informed of its experimental nature. Exclusion Criteria: * History of repeated strokes with stepwise progression of parkinsonian features * History of repeated head injury * History of definite encephalitis * Oculogyric crises (unless drug-induced) * Neuroleptic treatment at onset of symptoms * Supranuclear gaze palsy * Cerebellar signs * Babinski sign * Presence of cerebral tumor or communicating hydrocephalus on CT scan * Sustained remission or negative response to an adequate dose of levodopa * Patients with parkinsonism other than Idiopathic PD