Pharmacokinetics of MB-102 and Use of the Non-invasive Optical Renal Function Monitor (ORFM) Device in Subjects With Normal and Impaired Renal Function and a Range of Skin Color Types

INCLUSION CRITERIA Main Criteria for Inclusion (Quantum Leap and Radiance device) * Age \> 22 years - male or female * Eligible female non-pregnant participants who are either not of childbearing potential or willing to use adequate contraception during the trial * Males must be willing to practice abstinence or utilize adequate contraception from dosing day to at least 7 days post dose * Participants willing to comply with study requirements * Participants who have signed an informed consent form * Normal or non-clinically significant screening and baseline 12-lead electrocardiogram (ECG) in the opinion of the principal investigator (PI) * Adequate venous access sufficient to allow blood sampling per protocol requirements Main Criteria for Inclusion (Brilliance device) * Age \> 18 years - male or female * Eligible female non-pregnant participants who are either not of childbearing potential or willing to use adequate contraception during the trial * Males must be willing to practice abstinence or utilize adequate contraception from dosing day to at least 7 days post dose * Participants willing to comply with study requirements * Participants who have signed an informed consent form * Normal or non-clinically significant screening and baseline 12-lead ECG in the opinion of the PI * Adequate venous access sufficient to allow blood sampling per protocol requirements Normal-CKD Stage 2/QuantumLeap; Normal-CKD Stage 2/Radiance; Normal-CKD Stage 2/Brilliance algorit…