CompletedNot Applicable

SACRED A Prospective Research Study to Reduce Stroke in Children With Sickle Cell Anemia

Dominican Republic283 participantsStarted 2016-03-16

Plain-language summary

Prospective screening and treatment study for children with Sickle Cell Anemia and increased stroke risk living in the Dominican Republic.

Age range3 Years – 15 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

✕. Anemia: Hemoglobin concentration \< 6.0 gm/dL
✕. Reticulocytopenia: Absolute reticulocyte count \< 100 x 10˄9/L with a hemoglobin concentration \< 8.0 gm/dL
✕. Neutropenia: Absolute neutrophil count (ANC) \< 1.0 x 10˄9/L
✕. Thrombocytopenia: Platelet count \< 80 x10˄9 /L
✕. Known abnormal renal function (serum creatinine \>2X upper limit for age AND ≥ 1.0 mg/dL)

Transcranial Doppler Ultrasound examinations

Timeframe: 0-24 months

NCT IDNCT02769845

SponsorChildren's Hospital Medical Center, Cincinnati

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-07-01