CompletedNot Applicable

Influence of Indoor Air Filtration Strategies on Occupant Health Indicators

China89 participantsStarted 2014-11

Plain-language summary

The purpose of this study is to evaluate whether two different central air purification technologies reduce air pollutant exposure and beneficially influence health as evaluated with a suite of biological markers related to cardiovascular and respiratory disease risk.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Healthy adults; * Live and work at the Broad Town work campus in eastern Changsha, Hunan Province, China Exclusion Criteria: * Has any of the following diseases: chronic respiratory, cardiovascular, liver, renal, hematological disease; diabetes mellitus; * Has any other diseases that may confound or complicate the effects of the intervention * Pregnant females

What they're measuring

Change from baseline FEV1

Timeframe: At baseline, 2 weeks and 4 weeks into the intervention period, and then 2 weeks post-intervention

Change from baseline soluble P-selectin

Timeframe: At baseline, 2 weeks and 4 weeks into the intervention period, and then 2 weeks post-intervention

Change from baseline von Willebrand factor (VWF)

Timeframe: At baseline, 2 weeks and 4 weeks into the intervention period, and then 2 weeks post-intervention

Change from baseline augmentation index (AI)

Timeframe: At baseline, 2 weeks and 4 weeks into the intervention period, and then 2 weeks post-intervention

Change from baseline systolic blood pressure (SBP)

Timeframe: At baseline, 2 weeks and 4 weeks into the intervention period, and then 2 weeks post-intervention

Change from baseline fractional exhaled nitric oxide (FeNO)

Timeframe: At baseline, 2 weeks and 4 weeks into the intervention period, and then 2 weeks post-intervention

Trial details

NCT IDNCT02769208

SponsorFeng Li

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2015-01

View on ClinicalTrials.gov More Risk Factors for Respiratory and Cardiovascular Disease trials

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Change from baseline FEV1

Timeframe: At baseline, 2 weeks and 4 weeks into the intervention period, and then 2 weeks post-intervention

Change from baseline soluble P-selectin

Timeframe: At baseline, 2 weeks and 4 weeks into the intervention period, and then 2 weeks post-intervention

Change from baseline von Willebrand factor (VWF)

Timeframe: At baseline, 2 weeks and 4 weeks into the intervention period, and then 2 weeks post-intervention

Change from baseline augmentation index (AI)

Timeframe: At baseline, 2 weeks and 4 weeks into the intervention period, and then 2 weeks post-intervention

Change from baseline systolic blood pressure (SBP)

Timeframe: At baseline, 2 weeks and 4 weeks into the intervention period, and then 2 weeks post-intervention

Change from baseline fractional exhaled nitric oxide (FeNO)

Timeframe: At baseline, 2 weeks and 4 weeks into the intervention period, and then 2 weeks post-intervention