CompletedPhase 2/3

Green Coffee Extract and Metabolic Syndrome

Iran43 participantsStarted 2016-12-01

Plain-language summary

Metabolic syndrome (Mets) is an assemblage of risk factors which can increase the risk of developing type 2 diabetes mellitus and cardiovascular disease. Green coffee extract (GCE) is derived from unroasted coffee beans and has substantial amounts of polyphenols primarily chlorogenic acids (CGA). It has been shown that GCE and CGA can exert a positive influence over Mets components including blood pressure, blood glucose, inflammation, oxidative stress, insulin resistance and blood lipids. Up to our knowledge no study has been conducted on humans in the field of GCA influences on Mets patients. Therefore, this study is planned to evaluate GCA supplementation effects on anthropometric measurements, glycemic control, blood pressure, lipid profile in patients with metabolic syndrome.

Who can participate

Age range18 Years – 70 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Waist circumference\>102 cm in men and \>88 cm in women * Fasting blood glucose\>100 mg/dL (5.6 mmol /L) * Systolic blood pressure\>130 mmHg or diastolic blood pressure\>85mmHg * Triglycerides\> 150 mg/dL (1.7 mmol/L) Exclusion Criteria: * Insulin administration * Pregnancy and breastfeeding * regular consumption of coffee and green tea

What they're measuring

fasting blood glucose

Timeframe: 8 weeks

Trial details

NCT IDNCT02764957

SponsorNational Nutrition and Food Technology Institute

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-03-21

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