Predictive Value of DICA in the Diverticular Disease of the Colon (NCT02758860) | Clinical Trial Compass
CompletedNot Applicable
Predictive Value of DICA in the Diverticular Disease of the Colon
Brazil, Italy2,215 participantsStarted 2016-06
Plain-language summary
The Diverticular Inflammation and Complication Assessment (DICA) is an endoscopic classification for diverticulosis and diverticular disease of the colon.
The aim of the study is to show that DICA classification is a valid parameter to predict the risk of acute diverticulitis occurrence/recurrence and the need of surgery in patients suffering from diverticulosis/diverticular disease of the colon.
Who can participate
Age range18 Years
SexALL
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Inclusion Criteria:
* Endoscopic diagnosis of diverticula in the colon
Exclusion Criteria:
* • Radiological signs (by abdominal CT or by ultrasounds) of acute diverticulitis (complicated or uncomplicated)
* Inflammatory bowel diseases;
* Ischemic colitis;
* Prior colonic resection
* Patients with severe liver failure (Child-Pugh C);
* Patients with severe kidney failure;
* Pregnant women;
* Women of childbearing potential not using a highly effective method of contraception;
* Patients who are currently using or who have received any laxative agents \< 2 weeks prior to the enrollment;
* Patients who are currently using or who have received mesalamine compounds \< 2 weeks prior to the enrollment;
* Patients who are currently using or who have received any probiotic agents \< 2 weeks prior to the enrollment;
* Nonsteroidal anti-inflammatory drug (NSAID) use \< 1 week prior to the enrollment;
* Patients who have received treatment with antibiotics (even those not absorbed) \< 2 weeks prior to the enrollment;
* Inability to comply with study protocol and to give informed consensus to the procedure;
* Patients with or history of cancer, of any origin, within 5 years before enrollment
* History of alcohol, drug, or chemical abuse
* Any severe pathological condition that may interfere with the proper study execution.