A Phase III Study of Human Papillomavirus (HPV)-16/18 Vaccine.

Inclusion Criteria: * 18-30 healthy female * enable to provide an legal identification * have the ability to understand and sign the Informed Consent Form * confirmed by the investigator that the participant has the ability to comply with the protocol requirements * agreed to use effective contraceptive method in 7 months or has no plan of pregnancy * can avoid vaginal sex within two days (48 hours) before every interview; don't employ a vaginal douche or any other intervention which can influence the gynecological examination and sample collection Exclusion Criteria: * has received HPV vaccine previously; have received other research or unregistered product (drug or vaccine) within 30 days before the first injection * within three months before the first injection, has had received a whole-blood, plasma or immunoglobulin treatment, or planed to receive such treatments during the research period; within 28 days before the research, has had received attenuated live vaccine; or within 14 days has had received inactivated vaccine * has a history of allergic reaction which requires medical intervention; has allergic reaction for vaccine or vaccine-containing elements; has serious adverse effect history for vaccine * has a history of epilepsy, convulsion or has a family history of mental diseases * has immunodeficiency diseases including: AIDS, HIV infection, lymphoma, leukemia, Systemic Lupus Erythematosus, rheumatoid arthritis, Juvenile Rheumatoid Arthritis, inflammatory bowe…