Effect of Xpert MTB/RIF on Patient Outcomes (NCT02729532) | Clinical Trial Compass
CompletedNot Applicable
Effect of Xpert MTB/RIF on Patient Outcomes
Zambia776 participantsStarted 2016-06-22
Plain-language summary
A parallel-group prospective cohort study among adult persons living with HIV/AIDS to study the effect of a new TB diagnostic test, Xpert MTB/RIF on: 1) TB case detection; 2) time to TB diagnosis and TB treatment; 3) presumptive TB patient drop-out from the TB diagnostic "cascade" before starting TB treatment; and 4) loss to follow-up after initiation of TB treatment.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Exclusion criteria
unwilling or unable to provide verbal informed consent in English
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial looked at whether using the Xpert MTB/RIF test reduced the number of TB patients who dropped out before starting treatment — can you explain why patients with TB sometimes never make it to treatment, and how the test used in this study might have changed that?
2Since this trial is now completed, are the results available, and do they show that using Xpert MTB/RIF actually helped more patients with TB get connected to care compared to older testing methods?
3This study focused specifically on culture-positive TB patients — does that mean the findings would apply to my situation, or are there types of TB where this faster test matters more or less?
4The Xpert MTB/RIF test also detects rifampicin resistance — did this trial look at whether knowing about drug resistance early changed the treatment options patients received, and is that something relevant to my case?
5Given that this trial is already completed, is the Xpert MTB/RIF test now part of standard TB care where we are, or is there still a reason it might not be available to me?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Culture-positive patient drop-out before accessing treatment
Timeframe: From study enrolment through confirmed drop out date at or before 210-days post enrollment