Molecular, Histologic, and Clinical Analysis of Negative Pressure Wound Therapy (NPWT) for Split-thickness Skin Graft (STSG) Donor Sites

Inclusion Criteria: * Age 18-60 * Both genders are eligible for study * Written consent obtained from the subject or agent * Donor site wounds must not exceed 5% total body surface area (TBSA) * Subject must be receiving a split-thickness skin graft (STSG) * Donor site is amenable to either NPWT or standard of care (occlusive dressing) * Ability to comply with necessary wound care/follow up Exclusion Criteria: * Age \<18 years * Subject has been diagnosed with Diabetes * Subject is a smoker * Subject takes steroids * Subject takes immunosuppressive medications * Subject with immunosuppressive disorders * Donor site wounds that exceed 5% total body surface area (TBSA) * Subject has sensitivity to silver or acrylic adhesives * Inability to comply with necessary wound care/follow up.