The goal of this project is to utilize stable isotopically labeled vitamin D3 and state of the art mass spectrometric methodology to assess vitamin D dynamics during pregnancy in relation to relation to obesity and vitamin D binding protein genotype. At the conclusion of this study, the investigators will have obtained novel information on the absorption and utilization of vitamin D in women and the degree to which vitamin D utilization during pregnancy is impacted by genetic ancestry, vitamin D binding protein concentration and genotype and by excess adiposity. The long-term goal is to better understand the unique metabolism of vitamin D during pregnancy.
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Impact of pregnancy on serum vitamin D absorption
Timeframe: Across 40 days study period
Impact of obesity on vitamin D absorption
Timeframe: Across 40 days study period
Impact of ancestry on serum vitamin D absorption
Timeframe: Across 40 days study period