CompletedNot Applicable

Role of Geriatric Intervention in Treatment of Older Patients With Cancer (PREPARE)

France792 participantsStarted 2016-09-30

Plain-language summary

Randomized trials have already demonstrated that geriatric intervention was able to improve survival in the general elderly population but only a few have been performed in cancer patients. At the end, these data are not sufficient to consider geriatric intervention as validated in this setting. Case Management, coordinated by a geriatrician and a trained nurse, could improve prognosis of elderly patients with cancer. This approach, can be integrated in daily oncology practice. This strategy will be compared to usual oncological management in a randomized phase III trial.

Who can participate

Age range70 Years

SexALL

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Inclusion criteria

✓. Patient older 70 years and older
✓. Performance status 0 to 3 (WHO)
✓. G8 and QLQ-C30 questionnaires 'score are available
✓. No previous geriatric evaluation during cancer treatment
✓. Locally advanced or metastatic disease :
✓. 1st line medical treatment :
✓. Or 2nd line medical treatment :
✓. Life expectancy over 6 months

Exclusion criteria

✕. Patient who already received 2 medical treatment lines
✕. Exclusive 1st or 2nd treatment lines of :
✕. "Best supportive care" treatment
✕

What they're measuring

Overall survival defined as the delay between randomization and death, all causes.

Timeframe: Year 1

Health related quality of life (HR-QoL) assessed using 3 scales of European Organisation for Research and Treatment of Cancer (EORTC) QLQ-C30 questionnaire.

Timeframe: Year 1

Trial details

NCT IDNCT02704832

SponsorInstitut Bergonié

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-12-31

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