Durolane SJ for Treatment of Rhizarthrosis

Inclusion Criteria: * Subjects of both sexes aged 18 to 75 years. * Diagnosis of Grade II-III rhizarthrosis in either hand, according to the criteria of Eaton and Littler. * TMC joint pain lasting longer than 6 months and baseline pain value greater than or equal to 4 on the VAS scale (0 to 10) and less than 4 in the contralateral hand joint if there is pain. Exclusion Criteria: * Anticoagulant medication * Rheumatic disease involving the wrist, hand and fingers, such as rheumatoid arthritis or gout * Active rheumatoid arthritis * Previous surgery of the hand * Systemic infectious processes * Neoplastic disease * Subjects with contraindications to hyaluronic acid * Subjects with known hypersensitivity to hyaluronic acid or any of the components of the preparation under study * Previous hyaluronic acid injections in the hand * Subjects likely to miss the clinical follow-up visits * Taking of analgesics 24 hours before scheduled clinical assessments * Pregnant subjects * Any condition that in the opinion of the physician recommends exclusion of the subject