Prospective Randomized Trial About THD Versus Ligasure Hemorrhoidectomy for Grade III and IV Hemo… (NCT02654249) | Clinical Trial Compass
CompletedNot Applicable
Prospective Randomized Trial About THD Versus Ligasure Hemorrhoidectomy for Grade III and IV Hemorrhoids
Spain80 participantsStarted 2015-12
Plain-language summary
The study evaluates postoperative pain, morbidity, recurrence and quality of life, comparing two different strategies in the treatment of grade III and IV hemorrhoids: transanal hemorrhoidal dearterialization with mucopexy (THD) versus hemorrhoidectomy by Ligasureâ„¢.
Who can participate
Age range18 Years – 76 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients with grade III and IV hemorrhoids according to Goligher classification
* Patients ASA I, II or III and adequate hematological, renal and hepatic function
* Patients who signed informed consent
Exclusion Criteria:
* Altered cognitive state that prevents collaboration in the study or patients who can neither read nor write
* Fecal incontinence
* Anal sphincter lesions
* Recurrent hemorrhoids after previous surgical tratment
* Previous anorectal surgery except banding, botulinum toxin injection and thrombectomy for hemorrhoid thrombosis
* Injection sclerotherapy during the last five years
* Concomitant anorectal disease (anal fistula, anal fissure, anal stenosis, rectocele, enterocele, anal condilomatosis).
* Concomitant diagnosis of functional pelvic floor disease, inflammatory bowel disease and previous pelvic radiotherapy
* Concomitant diagnosis of colorectal neoplasia or other neoplasia
* Patients ASA IV, V
* NSAIDs, Paracetamol, Tramadol, Metamizol and Petidine allergy
* Coagulation disorders
* Pregnancy and lactation
* Rejection of the patient to sign the consent form.