Does in Vivo Culture of Pre-cleavage Stage Embryo Reduce the Incidence of Aneuploidy? (NCT02652143) | Clinical Trial Compass
TerminatedNot Applicable
Does in Vivo Culture of Pre-cleavage Stage Embryo Reduce the Incidence of Aneuploidy?
Stopped: Terminated due to difficult recruitment
Spain35 participantsStarted 2016-01
Plain-language summary
This Clinical Study has been designed to assess and compare the impact of in vitro or in vivo culture conditions on the euploidy of sibling blastocysts.
Who can participate
Age range18 Years – 38 Years
SexFEMALE
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Inclusion Criteria:
* Signed Informed Consent by the subject and her partner
* Women, aged between 18 and 38 years (up to 38th birthday)
* ≤ 2 previous stimulation cycles
* Routinely measured hormonal levels within normal range (i.e. FSH, LH, E2, PRL)
* No uterine or ovarian anatomical abnormalities and/or alterations that would compromise device delivery or function in the uterus as demonstrated by ultrasound and trial insertion
* 19 ≤ BMI ≤ 29 kg/m2
Exclusion Criteria:
* History of previous moderate or severe ovarian hyperstimulation syndrome (OHSS)
* Severe endometriosis
* Any active infection that would contraindicate ART, at the discretion of the investigator
* Severe male factor in the partner (cryptozoospermia or non-obstructive azoospermia)
What they're measuring
1
Euploidy status after a biopsy on all viable day 5 embryos