The Physiological Impact of CTO PCI on Coronary Pressure Measurements and Correlation in Donor Ve… (NCT02643940) | Clinical Trial Compass
CompletedNot Applicable
The Physiological Impact of CTO PCI on Coronary Pressure Measurements and Correlation in Donor Vessel
United Kingdom42 participantsStarted 2015-10-01
Plain-language summary
This study will be recording pressure wire readings from both blocked and narrowed arteries, to better guide treatment options; medications, stents or potentially bypass surgery, for patients with Chronic Total Occlusion (CTO).
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. Age \>18 years of age
✓. Stable angina / ischaemic symptoms
✓. Evidence of viability and / or ischaemia in the chronic total occlusion (CTO) territory
✓. Participant is willing and able to give informed consent for participation in the study
✓. Presence of a chronic total occlusion (CTO) in RCA:
✓. Presence of minor to intermediate coronary stenosis (1-70 %) in the contralateral donor artery
✓. Eligible for PCI to a chronic total occlusion (CTO)
Exclusion criteria
✕. Previous CABG with patent grafts to the interrogated donor artery
✕. Left main stenosis of \> 40 %
✕. Presence of severe flow limiting stenosis in the contralateral donor artery (typically \> 70 % stenosis)
✕. Haemodynamic instability at the time of intervention (heart rate \<40 beats per minute, systolic blood pressure \<90mmHg), balloon pump)
✕. Significant contraindication to adenosine administration (e.g. heart block, severe asthma)