The Physiological Impact of CTO PCI on Coronary Pressure Measurements and Correlation in Donor Ve… (NCT02643940) | Clinical Trial Compass
CompletedNot Applicable
The Physiological Impact of CTO PCI on Coronary Pressure Measurements and Correlation in Donor Vessel
United Kingdom42 participantsStarted 2015-10-01
Plain-language summary
This study will be recording pressure wire readings from both blocked and narrowed arteries, to better guide treatment options; medications, stents or potentially bypass surgery, for patients with Chronic Total Occlusion (CTO).
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Age \>18 years of age
. Stable angina / ischaemic symptoms
. Evidence of viability and / or ischaemia in the chronic total occlusion (CTO) territory
. Participant is willing and able to give informed consent for participation in the study
. Presence of a chronic total occlusion (CTO) in RCA:
. Presence of minor to intermediate coronary stenosis (1-70 %) in the contralateral donor artery
. Eligible for PCI to a chronic total occlusion (CTO)
Exclusion criteria
. Previous CABG with patent grafts to the interrogated donor artery
. Left main stenosis of \> 40 %
. Presence of severe flow limiting stenosis in the contralateral donor artery (typically \> 70 % stenosis)
. Haemodynamic instability at the time of intervention (heart rate \<40 beats per minute, systolic blood pressure \<90mmHg), balloon pump)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.