The Effect of Combined Surgery in Management of Congenital Pseudarthrosis of Tibia

Inclusion Criteria: * The inclusion criteria consists of patients with congenital pseudarthrosis of Tibia Exclusion Criteria: * Patients are complicated with mental, neurological disorders (such as hypoxic-ischemic encephalopathy, epilepsy and dementia) or significant barriers to growth. * Patients with pseudarthrosis of tibia caused by trauma, tumor,infection, etc * Children are complicated with dysfunction of liver and kidney , blood disorders, immune deficiency disease and ECG abnormalities. * Parents refused further treatment.