A Trial of IW-3718 for 8 Weeks in Patients With Symptomatic Gastroesophageal Reflux Disease (GERD)

Inclusion Criteria: * Patient is an ambulatory, community-dwelling male or nonpregnant female and is at least 18 years old at the Screening Visit. Lactating females must agree not to breastfeed. * Patient has a diagnosis of GERD and reports experiencing GERD symptoms (heartburn or regurgitation) on ≥ 4 days per week during the 8 weeks before the Screening Visit while taking standard QD PPI therapy. Exclusion Criteria: * Patient may not meet any of the excluded conditions specified in the protocol * Patient has any alarm symptoms including but not limited to GI bleeding, anemia, vomiting, dysphagia, or unexpected weight loss any time during the Screening or Pretreatment Periods * Patient has a history of clinically significant hypersensitivity or allergies to any of the excipients contained in the study medication (active or placebo). NOTE: Additional inclusion/exclusion criteria may apply.