Transcranial Magnetic Stimulation for Facial Pain (NCT02633306) | Clinical Trial Compass
CompletedNot Applicable
Transcranial Magnetic Stimulation for Facial Pain
United States9 participantsStarted 2016-08-01
Plain-language summary
Complex oro-facial pain is a poorly diagnosed and poorly treated cause of significant suffering and disability. This study will explore the ability of fMRI to identify patients with complex oro-facial pain who respond to transcranial magnetic stimulation therapy.
Specific Aims:
1. To establish baseline patterns of MRI in patients with chronic oro-facial pain without a definitive etiologic diagnosis.
2. To estimate the rate of treatment success of transcranial stimulation of the primary motor cortex (M1) in these patients.
3. To identify post-treatment MRI patterns that are associated with treatment success.
Who can participate
Age range18 Years – 110 Years
SexALL
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Inclusion Criteria:
* Age between 18 and 110
* Diagnosis of complex oro-facial pain made by the UMPhysicians Complex Facial Pain Clinic
* Alternative treatment of proven value not available as judged by the UMPhysicians Complex Facial Pain clinic
* One of the following types of facial pain as assessed by the Burchiel Patient Pain Rating Classification Questionnaire:
* trigeminal neuralgia Type 2 (TN2)
* trigeminal neuropathic pain (TNP)
* trigeminal deafferentation pain (TDP)
* post herpetic neuralgia (PHN)
* atypical facial pain (AFP)
* nervus intermedius neuralgia (NIN)
* Willing and able to give informed consent
Exclusion Criteria:
* Subject diagnosed according to the MINI as suffering from any other major Axis I disorder, such as Psychotic Disorder, Bipolar affective disorder, OCD (MDD is not contraindicated when Hamilton Depression Rating Scale -21≤26, or Beck Depression Inventory).
* Subjects with significant suicidal risk as assessed by the investigator using the Beck Suicide Ideation scale, psychiatric interview or a history of attempted suicide in the past year.
* Subject has a history of epilepsy or seizure (EXCEPT those therapeutically induced by ECT).
* Subject has a history of significant head trauma with loss of consciousness for longer than 5 minutes.
* Subject has a history of cranial surgery within 1 month of treatment.
* Subject has metallic particles in the eye or head (exclusive of mouth), implanted cardiac pacemaker or any intra-cardiac li…