Radiation Therapy in Treating Patients With Hepatocellular Carcinoma, Cholangiocarcinoma, or Liver Metastasis Who Have Impaired Liver Function

Inclusion Criteria: * Diagnosis of hepatocellular carcinoma, cholangiocarcinoma, or liver metastasis from any histology * Patients may have single or multinodular tumors * There is no specific tumor size cut-off for this protocol; however, the radiation treatment plan must meet the protocol's dose constraints * Compromised liver function as defined by any of the following: * Cohort 1: Advanced cirrhosis group * Borderline Child-Pugh class A6 * Child-Pugh class B * The patients in this advanced cirrhosis group must have at least 400 ml of functional liver, as estimated on either diagnostic imaging (computed tomography \[CT\] or magnetic resonance imaging \[MRI\]) or single photon emission computed tomography (SPECT)/CT with Tc-99m sulfur colloid; there is no upper limit on the functional liver volume for these patients * Cohort 2: Low functional liver volume without underlying chronic liver disease * Previous irinotecan or oxaliplatin chemotherapy * Previous liver resection(s) * These patients must have at least 400 ml of functional liver, as estimated by either diagnostic imaging computed tomography or magnetic resonance imaging (CT or MRI) or SPECT/CT with Tc-99m sulfur colloid; there is no upper limit on the functional liver volume for these patients; * Cohort 3: History of prior liver-directed radiation therapy with either fractionated external beam radiation therapy (EBRT), stereotactic body radiation therapy (SBRT) or yttrium-90 ra…