Investigate the Radical Extent of Lymphadenectomy of LAparoscopic Right Colectomy for Colon Cance… (NCT02619942) | Clinical Trial Compass
UnknownNot Applicable
Investigate the Radical Extent of Lymphadenectomy of LAparoscopic Right Colectomy for Colon Cancer(RELARC).
China1,072 participantsStarted 2016-01-09
Plain-language summary
To investigate whether extended lymphadenectomy (CME) in laparoscopic colectomy could improve disease-free survival in patients with right colon cancer, compared with standard D2 radical operation.
Who can participate
Age range18 Years – 75 Years
SexALL
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Inclusion criteria
✓. Patients suitable for curative surgery 18-75years old
✓. ASA grade I-III
✓. Qualitative diagnosis: a pathological diagnosis of adenocarcinoma;
✓. Localization diagnosis: the tumor located between the cecum and the right 1/3 of transverse colon;
✓. Enhanced CT scan of chest, abdominal and pelvic cavity: assessment of tumor stage is T2-T4N0 or TanyN+; there is no distant metastasis.
✓. Informed consent
Exclusion criteria
✕. Simultaneous or simultaneous multiple primary colorectal cancer;
✕. Preoperative imaging examination results show: (1) colon cancer of stage T1N0; (2) enlargement of lymph node at the root of mesocolon, in which case the D3 radical operation must be performed;
✕. Preoperative imaging examination results show: (1) Tumor involves the surrounding organs and combined organ resection need to be done; (2)distant metastasis; (3)unable to perform R0 resection;
✕. History of any other malignant tumor in recent 5 years, except for cervical carcinoma in situ which has been cured, basal cell carcinoma or squamous cell carcinoma of skin;
✕. Patients need emergency operation;
✕. Not suitable for laparoscopic surgery (i.e., extensive adhesion caused by abdominal surgery, not suitable for artificial pneumoperitoneum, etc).