Evaluating RXI-109 to Reduce the Progression of Subretinal Fibrosis in Subjects With NVAMD

Inclusion Criteria: * Subjects presenting with advanced NVAMD in the study eye with BCVA ≤20/100 potentially due to subretinal fibrosis involving the fovea * BCVA ≥20/800 in the contralateral eye and better than the study eye * ≥50 years of age * Subfoveal choroidal neovascularization (CNV) of any type Exclusion Criteria: * Presence of other causes of CNV including pathologic myopia, ocular histoplasmosis syndrome, angioid streaks, choroidal rupture, and multifocal choroiditis * Evidence of inflammation (Grade 1 or higher) in the anterior or posterior chamber