A Safety and Activity Study of NS2 in Subjects With Allergic Conjunctivitis

Inclusion Criteria: * Graded conjunctival redness in at least one region (nasal or temporal) in each eye at any one time point (not necessarily the same time point) post-CAPT (Conjunctival Allergen Provocation Test) of \>2 * Graded ocular itching at any one time point * Visual acuity of at least 20/50 in each eye * At least 2 year history of moderate to severe allergic conjunctivitis. * Positive skin prick test to ragweed, grass and/or tree pollen within one year of Screening Visit (Visit 1). * Ability to avoid any topical or systemic ocular medications during the entire study period. Exclusion Criteria: * Subjects must not have an ocular itching score \>0 or a conjunctival redness score \>1 prior to CAPT in either eye in any region (nasal or temporal) at Visits 2-4. I * History of glaucoma, or Intraocular Pressure (IOP) over 25mmHg at the screening visit, or a history of elevated IOP within the past 1 year. * Ocular surgery, including laser procedures, within the past 12 months of Visit 1. * Use of glaucoma medications, antibiotics, antivirals, or topical cyclosporine within 1 month of the screening visit. * History of dry eye syndrome, blepharitis, herpes simplex keratitis or herpes zoster keratitis. * History of uveitis in the past 3 years. * Presence of any ocular infection or active ocular inflammation (e.g. follicular conjunctivitis, allergic conjunctivitis) within 14 days prior to start of study (Visit 1). * History of moderate to severe asthma or allergy induced as…