Patients with active Axial Spondyloarthritis without x-ray evidence of Ankylosing Spondylitis and with signs of inflammation will be randomly assigned to receive certolizumab pegol (CZP) 200 mg every two weeks or placebo. The primary objective is to demonstrate the efficacy of CZP in these patients.
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Percentage of Subjects With Ankylosing Spondylitis Disease Activity Score Major Improvement (ASDAS-MI) Response Criteria Response at Week 52
Timeframe: Week 52
Percentage of Subjects With Axial SpondyloArthritis International Society 40% Response Criteria (ASAS40) Response at Week 12
Timeframe: Week 12
Certolizumab Pegol Plasma Concentration at Baseline
Timeframe: Baseline (Week 0)
Certolizumab Pegol Plasma Concentration at Week 1
Timeframe: Week 1
Certolizumab Pegol Plasma Concentration at Week 2
Timeframe: Week 2
Certolizumab Pegol Plasma Concentration at Week 4
Timeframe: Week 4
Certolizumab Pegol Plasma Concentration at Week 12
Timeframe: Week 12
Certolizumab Pegol Plasma Concentration at Week 24
Timeframe: Week 24
Certolizumab Pegol Plasma Concentration at Week 36
Timeframe: Week 36
Certolizumab Pegol Plasma Concentration at Week 52
Timeframe: Week 52
Certolizumab Pegol Plasma Concentration at Follow-Up (FU) Visit
Timeframe: Follow-up Visit (up to Week 60)