Clinical Study to Evaluate the Safety and Performance of MANTA Vascular Closure Device

Inclusion Criteria: * Candidate for non-emergent transcatheter interventional procedure via a 10-18F femoral sheath (e.g., transcatheter aortic valve replacement \[TAVR\], balloon aortic valvuloplasty \[BAV\], Abdominal Aortic Aneurysm \[AAA\] stent-graft placement) * Eligible for sheath removal in the catheterization lab * Age ≥18 years * Understand and sign the study specific written informed consent form * Able and willing to fulfill the follow-up requirements * In the Investigator's opinion, the patient is suitable for the MANTA vascular closure device, conventional hemostasis techniques and participation in an investigational trial * Patients of childbearing age with Negative Pregnancy Test within 7 days of procedure Exclusion Criteria: Baseline Exclusions: * Patients who are known to be pregnant or lactating * Patients who are immunocompromised or with pre-existing autoimmune disease * Patients who have a systemic infection or a local infection at or near the access site * Patients requiring a re-puncture at a site previously punctured within 48 hours * Patients with significant anemia (hemoglobin \< 6.5 mmol/l, Hct\<30) * Patients who are morbidly obese or cachectic (BMI \>40 or \<20) * Patients with Systolic Blood Pressure \>180 mmHg, unless Systolic Pressure can be lowered by pharmacological agents prior to closure * Patients who are currently participating in another clinical trial of an investigational device or drug that has not concluded the follow-up period …