TerminatedNot Applicable

Echocardiography for RILI Prediction

Stopped: The study is prematurely terminated due to bad inclusion and the fact that examinations are already being used in standard care.

Netherlands15 participantsStarted 2017-04-25

Plain-language summary

Severe radiation-induced lung injury (RILI) occurs in approximately 20% of the lung cancer patients, who are treated with curative chemoradiation. In this study the investigators want to evaluate the prognostic value of baseline cardiac function assessed with echocardiography for prediction of RILI.

Who can participate

Age range18 Years

SexALL

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Inclusion Criteria: * Clinical stage I-III non small cell lung cancer, excluding malignant pleural/pericardial effusion * Planned for curatively intended primary (chemo)radiotherapy, due to irresectable disease and/or medical inoperability * WHO performance status 0-2 * No history of prior chest radiotherapy * No uncontrolled infectious disease * No other active malignancy * No prior lung surgery (VATS, wedge resection, segment resection, lobectomy) * Willing and able to comply with the study prescriptions * 18 years or older * Ability to give and having given written informed consent before patient registration Exclusion Criteria: * malignant pleural/pericardial effusion * history of prior chest radiotherapy * uncontrolled infectious disease * other active malignancy * prior lung surgery (VATS, wedge resection, segment resection, lobectomy)

What they're measuring

Dyspnea score at three months after (chemo)radiotherapy, assessed by the patient version of the CTCv4.0

Timeframe: up to 3 months

Trial details

NCT IDNCT02501707

SponsorMaastricht Radiation Oncology

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2019-09-12

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