TOP-TRIAL Safety of Not Flushing Non-used PORT-A-CATH® in Cancer Patients

Inclusion Criteria: * Cancer patients in curative setting, with port a cath Implantation for systemic chemotherapy, including neo-adjuvant and adjuvant chemo-immunotherapy and supportive therapy (e.g. parenteral Nutrition) * Completion of curative Treatment with port a cath indication, operation included, regardless of a non-intravenous (subcutaneous or oral) given therapy (endocrine therapy, chemo-immunotherapy, radiotherapy) * patients with pectoral port a cath systems * No port a cath associated complications during curative therapy such as investigated events: persistent malfunction, thrombosis, infection of the port-a-cath (to puncture the port a cath under X-ray control is allowed except it results in diangosis of persistent malfunction) * No therapeutic anticoagulant therapy (phenprocoumon/Marcoumar®, heparin) * No evidence of metastatic disease * ≥18 years * Willing to participate Exclusion Criteria: * No signed informed consent * Patients with port a cath systems other than pectoral port a cath systems (e.g. forearm port a cath System) * Unable to attend control timepoints * Use of the port-a-cath after the above defined curative treatment (within the investigational period) * Willing to explant the port-a-cath * Willing to become pregnant within one year after adjuvant treatment * Patient with heparin-induced Thrombocytopenia (HIT)